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Symbol
Name
ID

Havcr1
hepatitis A virus cellular receptor 1
MGI:2159680

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Allergic rhinitis	Conjunctivitis	Eczematoid dermatitis	Atopic dermatitis	Recurrent skin infections	Asthma
Disease(s) Associated with HAVCR1
atopic dermatitis

Mouse Phenotypes

immune system phenotype

enlarged spleen

increased spleen weight

abnormal T cell differentiation

increased double-negative T cell number

increased eosinophil cell number

increased neutrophil cell number

increased CD4-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

increased T cell number

increased activated T cell number

decreased lymphocyte cell number

increased lymphocyte cell number

abnormal B cell physiology

abnormal CD4-positive, alpha-beta T cell physiology

abnormal dendritic cell physiology

abnormal cytokine secretion

increased interferon-gamma secretion

abnormal interleukin secretion

increased interleukin-10 secretion

increased interleukin-13 secretion

increased interleukin-17 secretion

increased interleukin-4 secretion

increased interleukin-5 secretion

increased tumor necrosis factor secretion

autoimmune response

increased anti-double stranded DNA antibody level

abnormal inflammatory response

respiratory system inflammation

Availability

Mouse Genotype

Havcr1^tm1Kuch/Havcr1^tm1Kuch

Havcr1^tm1Shw/Havcr1^tm1Shw

*

Havcr1^tm1Vlcg/Havcr1^tm1Vlcg

*

Timd2^{tm1(GAL4)Pdre}/Timd2^{tm1(GAL4)Pdre}

Timd6^{tm1b(KOMP)Wtsi}/Timd6⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23